However, controlling for total M-CHAT failures, this male disadvantage was more equivocal and many classically ASD-associated features were found more common in non-ASD.Within ASD, females showed relative strengths in joint attention, but impairments in imitation.
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) suggested ASD could be considered an extreme expression of normal male, compared to female, phenotypic profiles.
In this paper, sex-specific M-CHAT scores from N = 53,728 18-month-old toddlers, including n = 185 (32 females) with ASD, were examined.
Results suggest a nuanced view of the “extreme male brain theory of autism”.
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